Light-triggered conversion of non-ionic into ionic surfactants: towards chameleon detergents for 2-D gel electrophoresis.

نویسندگان

  • Oliver Bogen
  • Petar Milosevic
  • Hans Daroszi
  • Mathias Dreger
  • Stefan Hecht
  • Ferdinand Hucho
چکیده

Caged non-ionic detergents, comprised of polar oligo(ethylene glycol) and non-polar alkyl chains joined by a photocleavable ortho-nitrobenzyl sulfonate linker have been synthesized and characterized. The light-triggered transformation of such chameleon surfactant from a charge-neutral into a charged form offers great potential to improve 2-D gel electrophoretic separation of complex protein mixtures.

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عنوان ژورنال:
  • Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

دوره 11 3  شماره 

صفحات  -

تاریخ انتشار 2012